Microcrystalline Cellulose

Microcrystalline Cellulose carries a safety score of 3/5 and appears in 1,187 indexed US food products.

Safety score 60.0%

3/5 from FDA SAFFA + CSPI Chemical Cuisine

How common is vs other flagged additives?

Number of indexed products containing each of the most common flagged additives — Microcrystalline Cellulose highlighted.

Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.

Caramel Coloring22612Red 4021595Yellow 518987Carrageenan17853Blue 116643Yellow 613560Sucralose10490Microcrystalline Cellulose1187
Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.
Safety Score
3/5

Safety Assessment

Microcrystalline Cellulose has a moderate safety profile (3/5). While approved for use, some studies or consumer advocacy groups have raised questions about certain aspects of this ingredient. Consumers who prefer caution may wish to limit intake.

What the Data Says About

Microcrystalline Cellulose currently appears in 1,187 products across the OpenFoodFacts catalog we index, which gives a concrete measure of its footprint on US grocery shelves. Our internal safety score of 3/5 synthesizes FDA Substances Added to Food (SAFFA) regulatory status with the Center for Science in the Public Interest (CSPI) Chemical Cuisine classification. These two frameworks capture different questions: regulators ask whether exposure at typical intake is acceptable, while consumer-advocacy groups examine cumulative dietary load and vulnerable-population risk.

Microcrystalline Cellulose serves one or more technical functions in food manufacturing — stabilization, flavor, preservation, or structural role — which explains its presence across multiple product categories in our database. Inspection and outbreak records frequently trace back to control failures around functional additives, whether through batch contamination, undisclosed substitutions, or labeling mismatches that trigger recall classifications by the FDA.

No specific concern flags are attached to Microcrystalline Cellulose in our current data snapshot beyond the regulatory and CSPI classifications above. That does not rule out individual sensitivity reactions, and anyone managing allergies, elimination diets, or chronic conditions should verify with a qualified healthcare professional before relying on population-level ratings.

Safety Profile at a Glance

Regulatory and safety classifications for Microcrystalline Cellulose
Source Classification Year
FDA SAFFA Not listed 2024
CSPI Chemical Cuisine Not rated 2024
PlainFoodSafe Score 3/5 2026
Product footprint 1,187 products OpenFoodFacts

FDA SAFFA database, CSPI Chemical Cuisine ratings, OpenFoodFacts product index. See methodology.

Products Containing

Showing 50 of 1,187 products

0016500579793
one a day
60/100
0681131433501
Unknown
85/100
1 mg melatonin
Natrol
100/100
10 flour tortillas
Unknown
100/100
10 Flour Tortillas
Schnucks
100/100
10 flour tortillas fajita style
Unknown
100/100
100% beef aminos
Unknown
100/100
100% whole wheat flour tortillas
Unknown
100/100
100% Whole Wheat Flour Tortillas
Unknown
100/100
100% whole wheat flour tortillas soft taco
Fit and Active
100/100
100% whole wheat tortillas, whole wheat
Unknown
100/100
4 Milk Chocolate Shakes
Nutrisystem Inc.
80/100
5-mthf 5 Mg Methylfolate
Thorne
100/100
6 CT WHITE & CHOCOLATE CUP WITH WHIPPED ICING
Walmart
0/100
6 presliced bagels, onion
Unknown
100/100
6\fajitaflourtortillas
Essential Everyday
100/100
7 keto dhea metabolite
Unknown
100/100
8 Greens
Unknown
100/100
8" Flour Tortillas
Prayers
100/100
8\softtacoflourtortillas
Unknown
100/100
acetaminophen arthritis
Unknown
95/100
acidophilus with pectin
Unknown
100/100
Advanced Hair + Nail Care
Biosil
100/100
Advanced Keratin For Hair, Skin And Nails
Vthrive The Vitamin Shoppe
100/100
Advanced Magnesium+
JSHealth
100/100
advantanced multi ea
Unknown
100/100
Advil
Unknown
85/100
aleve pm
Unknown
100/100
Algaecal Plus
AlgaeCal
100/100
Align Probiotic
Align
85/100
Align Probiotic
Unknown
70/100
All Day Focus
Unknown
100/100
Allegra
Allegra
100/100
allegra allergy
Unknown
100/100
Allegra d
Unknown
100/100
Allergy Extra Strength
Benadryl
80/100
allergy medications
alavert
70/100
allergy relief Aldi
Unknown
95/100
Amandine sauce mix
Unknown
100/100
Amazing Ashwa
Force Factor
100/100
Animal Pak Ultimate Foundation
Animal
100/100
Apple Bear Claws
Walmart
85/100
Apple Caramel Filled Muffins
The Bakery
100/100
Apple cider vinegar
Unknown
85/100
Apple coffee cake
Bakery Fresh Goodness
95/100
Apple danish coffee cake
Meijer
95/100
Apple muffins with apple pieces & caramel filling
Unknown
100/100
Apple strudel
Unknown
80/100
Artisan mini danish
Unknown
100/100
Ascorbyl Palmitate 500 Mg
NOW
100/100

Frequently Asked Questions

Is Microcrystalline Cellulose safe to eat?

Microcrystalline Cellulose has a safety score of 3/5. Always check with a healthcare provider if you have specific dietary concerns.

What products contain Microcrystalline Cellulose?

Microcrystalline Cellulose is found in 1,187 products in our database, spanning various food categories and brands.

What does Microcrystalline Cellulose do in food?

Microcrystalline Cellulose serves various technical functions in food manufacturing and processing.

Where does this ingredient safety data come from?

Safety data comes from the FDA's SAFFA (Substances Added to Food) database, CSPI (Center for Science in the Public Interest) ratings, and the OpenFoodFacts product database. Product counts reflect items cataloged in OpenFoodFacts.