Disodium Inosinate & Disodium Guanylate

Disodium Inosinate & Disodium Guanylate carries a safety score of 3/5 and appears in 227 indexed US food products.

Safety score 60.0%

3/5 from FDA SAFFA + CSPI Chemical Cuisine

How common is vs other flagged additives?

Number of indexed products containing each of the most common flagged additives — Disodium Inosinate & Disodium Guanylate highlighted.

Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.

Caramel Coloring22612Red 4021595Yellow 518987Carrageenan17853Blue 116643Yellow 613560Sucralose10490Disodium Inosinate & Disodium Guanylate227
Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.
Safety Score
3/5

Safety Assessment

Disodium Inosinate & Disodium Guanylate has a moderate safety profile (3/5). While approved for use, some studies or consumer advocacy groups have raised questions about certain aspects of this ingredient. Consumers who prefer caution may wish to limit intake.

What the Data Says About

Disodium Inosinate & Disodium Guanylate currently appears in 227 products across the OpenFoodFacts catalog we index, which gives a concrete measure of its footprint on US grocery shelves. Our internal safety score of 3/5 synthesizes FDA Substances Added to Food (SAFFA) regulatory status with the Center for Science in the Public Interest (CSPI) Chemical Cuisine classification. These two frameworks capture different questions: regulators ask whether exposure at typical intake is acceptable, while consumer-advocacy groups examine cumulative dietary load and vulnerable-population risk.

Disodium Inosinate & Disodium Guanylate serves one or more technical functions in food manufacturing — stabilization, flavor, preservation, or structural role — which explains its presence across multiple product categories in our database. Inspection and outbreak records frequently trace back to control failures around functional additives, whether through batch contamination, undisclosed substitutions, or labeling mismatches that trigger recall classifications by the FDA.

No specific concern flags are attached to Disodium Inosinate & Disodium Guanylate in our current data snapshot beyond the regulatory and CSPI classifications above. That does not rule out individual sensitivity reactions, and anyone managing allergies, elimination diets, or chronic conditions should verify with a qualified healthcare professional before relying on population-level ratings.

Safety Profile at a Glance

Regulatory and safety classifications for Disodium Inosinate & Disodium Guanylate
Source Classification Year
FDA SAFFA Not listed 2024
CSPI Chemical Cuisine Not rated 2024
PlainFoodSafe Score 3/5 2026
Product footprint 227 products OpenFoodFacts

FDA SAFFA database, CSPI Chemical Cuisine ratings, OpenFoodFacts product index. See methodology.

Products Containing

Showing 50 of 227 products

8 chicken pot pies
Unknown
90/100
814 americas, higueral, jamonada cooked salami
814 Americas
85/100
asian salad kit
Bonduelle
100/100
Asian sesame chopped salad kit
Unknown
100/100
Atlantic salmon with lemon pepper rub on a cedar plank
Unknown
100/100
Au Gratin Potatoes
Unknown
35/100
AWARD CUISINE Chicken And Dumplings, 95 OZ
Unknown
100/100
AWARD CUISINE Stuffed Cabbage With Beef In Tomato Sauce, 92 OZ
Unknown
95/100
Baby back ribs flavored potato chips, baby back ribs
Unknown
95/100
Bacon cheddar ranch breaded chicken breast cutlets
Unknown
100/100
BANQUET Homestyle Bake Chicken And Biscuits, 28.1 OZ
Unknown
100/100
BANQUET Homestyle Bakes Chicken Dumpling, 25.7 OZ
Banquet
80/100
BANQUET Homestyle Bakes Creamy Turkey, 25.7 OZ
Unknown
90/100
Banquet Mega Meals Salisbury Steak Frozen Dinner, 15.25 Ounce, 15.25 OZ
Unknown
80/100
BANQUET Salisbury Steak Dinner, 12.5 OZ
Unknown
80/100
Barbecue potato chips
Unknown
100/100
Barbecue potato chips
Unknown
100/100
Base granular low sodium beef natural
Unknown
95/100
Bbq Potato Chips
Valu Time, Topco
95/100
Bean & Cheese Burrito
7 Eleven
75/100
Beef & cheese mini tacos
Unknown
95/100
Beef and vegetables in a sweet hoisin sauce with steamed rice
Tai Pei, Windsor Quality Food Products Ltd.
95/100
Beef flavored broth base & seasoning, beef
Unknown
95/100
Beef Pho
Pholicious
100/100
Beef steak burrito
Don miguel
100/100
BERTOLLI Farfalle Carbonara, 10 OZ
Bertolli
95/100
Better made, special, potato chips, cheddar & sour cream
Better Made, Better Made Snack Foods Inc.
100/100
bigs
Bimbo
75/100
Bigs Sizzling Bacon Sunflower Seeds
Bigs
100/100
Breaded calamari rings
Unknown
100/100
Brim's Fiert Hot Onion Rings
Brim's
75/100
Broccoli & cheese rice mix
Unknown
100/100
Brookshire's, tortilla chips, lightly salted
Brookshire's, Brookshire Grocery Company
100/100
Broth Base & Seasoning
Orrington Farms
95/100
Broth Base & Seasoning, Ham Flavored
Orrington Farms
95/100
Buc-o’s snqck rings
Unknown
100/100
Buffalo hot wing almonds
Unknown
95/100
Buffalo ranch dip
Dean's
95/100
Buffalo ranch party bites premium puffed corn snacks, buffalo ranch
Unknown
100/100
Buffalo Seasoned Monterey Jack Cheese
Crystal Farms
100/100
bww
Unknown
100/100
Caesar salad
Unknown
80/100
California Roll
Zenshi
35/100
California Salad Roll
Zenshi
100/100
Cheese Dip
Tgi Fridays
100/100
Cheesy Jalapeño flavored curls
Unknown
50/100
Chef salad with turkey
Unknown
85/100
Chef swagger's kitchen, flavored sauce with fettuccine pasta, chicken
Chef Swagger's Kitchen
100/100
chef woo beef flavor ramen
Unknown
100/100
Chicken & Cheese Flautas
Don Miguel
100/100

Frequently Asked Questions

Is Disodium Inosinate & Disodium Guanylate safe to eat?

Disodium Inosinate & Disodium Guanylate has a safety score of 3/5. Always check with a healthcare provider if you have specific dietary concerns.

What products contain Disodium Inosinate & Disodium Guanylate?

Disodium Inosinate & Disodium Guanylate is found in 227 products in our database, spanning various food categories and brands.

What does Disodium Inosinate & Disodium Guanylate do in food?

Disodium Inosinate & Disodium Guanylate serves various technical functions in food manufacturing and processing.

Where does this ingredient safety data come from?

Safety data comes from the FDA's SAFFA (Substances Added to Food) database, CSPI (Center for Science in the Public Interest) ratings, and the OpenFoodFacts product database. Product counts reflect items cataloged in OpenFoodFacts.