Transglutaminase
Transglutaminase carries a safety score of 2/5 and appears in 15 indexed US food products. CSPI rates it “Caution.”
2/5 from FDA SAFFA + CSPI Chemical Cuisine
How common is Transglutaminase vs other flagged additives?
Number of indexed products containing each of the most common flagged additives - Transglutaminase highlighted.
Function
Other
Safety Assessment
Transglutaminase has a lower safety score (2/5), indicating notable concerns from food safety researchers or advocacy organizations. Individuals with sensitivities should consider alternatives. CSPI recommends limiting consumption of this ingredient.
What the Data Says About Transglutaminase
Transglutaminase currently appears in 15 products across the OpenFoodFacts catalog we index, which gives a concrete measure of its footprint on US grocery shelves. Our internal safety score of 2/5 synthesizes FDA Substances Added to Food (SAFFA) regulatory status with the Center for Science in the Public Interest (CSPI) Chemical Cuisine classification of "Caution." That Caution rating marks a gap between the two lenses: FDA's SAFFA status covers typical intake, while CSPI's review flags cumulative exposure across a modern diet as the open question this score doesn't resolve on its own.
In food manufacturing, Transglutaminase functions as a other. That technical role explains why it recurs across many product categories, formulators select specific additives for stability, shelf life, color, or texture performance, and substitution is rarely a one-for-one swap when regulations or consumer preferences shift. Inspection and outbreak data often trace back to breakdown in the control of exactly these kinds of functional ingredients, either through contaminated batches, undisclosed substitutions, or labeling errors that trigger FDA-initiated recalls.
No specific concern flags are attached to Transglutaminase in our current data snapshot beyond the regulatory and CSPI classifications above. That does not rule out individual sensitivity reactions, and anyone managing allergies, elimination diets, or chronic conditions should verify with a qualified healthcare professional before relying on population-level ratings.
Safety Profile at a Glance
| Source | Classification | Year |
|---|---|---|
| FDA SAFFA | Not listed | 2024 |
| CSPI Chemical Cuisine | Caution | 2024 |
| PlainFoodSafe Score | 2/5 | 2026 |
| Product footprint | 15 products | OpenFoodFacts |
FDA SAFFA database, CSPI Chemical Cuisine ratings, OpenFoodFacts product index. See methodology.
Products Containing Transglutaminase
A sample of 15 of the 15 indexed products containing Transglutaminase, with each product's overall safety score.
Frequently Asked Questions
Is Transglutaminase safe to eat? ▼
Transglutaminase has a safety score of 2/5. The Center for Science in the Public Interest (CSPI) rates it as "Caution." Always check with a healthcare provider if you have specific dietary concerns.
What products contain Transglutaminase? ▼
Transglutaminase is found in 15 products in our database, spanning various food categories and brands.
What does Transglutaminase do in food? ▼
Transglutaminase is used as a other in food products.
Citation notes
Regulatory status from FDA SAFFA; safety ratings from CSPI Chemical Cuisine; product presence from Open Food Facts. See our methodology. Retrieved and formatted by PlainFoodSafe Editorial.Every figure on PlainFoodSafe is rendered directly from OpenFoodFacts and FDA data, no number is typed in by an editor. Ingredient figures are computed directly from OpenFoodFacts, FDA SAFFA, and CSPI Chemical Cuisine data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of May 2026.