Microbial Enzyme

Microbial Enzyme carries a safety score of 3/5 and appears in 431 indexed US food products.

Safety score 60.0%

3/5 from FDA SAFFA + CSPI Chemical Cuisine

How common is vs other flagged additives?

Number of indexed products containing each of the most common flagged additives — Microbial Enzyme highlighted.

Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.

Caramel Coloring22612Red 4021595Yellow 518987Carrageenan17853Blue 116643Yellow 613560Sucralose10490Microbial Enzyme431
Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.
Safety Score
3/5

Safety Assessment

Microbial Enzyme has a moderate safety profile (3/5). While approved for use, some studies or consumer advocacy groups have raised questions about certain aspects of this ingredient. Consumers who prefer caution may wish to limit intake.

What the Data Says About

Microbial Enzyme currently appears in 431 products across the OpenFoodFacts catalog we index, which gives a concrete measure of its footprint on US grocery shelves. Our internal safety score of 3/5 synthesizes FDA Substances Added to Food (SAFFA) regulatory status with the Center for Science in the Public Interest (CSPI) Chemical Cuisine classification. These two frameworks capture different questions: regulators ask whether exposure at typical intake is acceptable, while consumer-advocacy groups examine cumulative dietary load and vulnerable-population risk.

Microbial Enzyme serves one or more technical functions in food manufacturing — stabilization, flavor, preservation, or structural role — which explains its presence across multiple product categories in our database. Inspection and outbreak records frequently trace back to control failures around functional additives, whether through batch contamination, undisclosed substitutions, or labeling mismatches that trigger recall classifications by the FDA.

No specific concern flags are attached to Microbial Enzyme in our current data snapshot beyond the regulatory and CSPI classifications above. That does not rule out individual sensitivity reactions, and anyone managing allergies, elimination diets, or chronic conditions should verify with a qualified healthcare professional before relying on population-level ratings.

Safety Profile at a Glance

Regulatory and safety classifications for Microbial Enzyme
Source Classification Year
FDA SAFFA Not listed 2024
CSPI Chemical Cuisine Not rated 2024
PlainFoodSafe Score 3/5 2026
Product footprint 431 products OpenFoodFacts

FDA SAFFA database, CSPI Chemical Cuisine ratings, OpenFoodFacts product index. See methodology.

Products Containing

Showing 50 of 431 products

100% Parmesan Grated Cheese
Kraft
100/100
2 year aged cheddar cheese
Balderson
100/100
3 Cheese Ravioli
Weis
95/100
3 Cheese Ravioli Durum Semolina & Egg Pasta Stuffed With 3 Cheeses
Weis Quality
95/100
3 color cheese tortellini
Unknown
100/100
3 color cheese tortellini
Unknown
100/100
4 cheese blend rising crust pizza
Unknown
100/100
4 Cheese Ravioli
Trader Joe's
100/100
4 Cheese Tortellini
O'Sole Mio
100/100
6 Cheese Tortellini
Weis
95/100
Alfredo sauce
Unknown
95/100
Alfredo sauce
Unknown
95/100
Alfredo Sauce
Harris Teeter
95/100
Ancient Grain & Seed Bread
Trader Joe's
100/100
Angus Beef Meatballs
Trader Joe's
100/100
Arancini
Alfredo
100/100
Archer farms, tomato florentine soup
Archer Farms, Target Stores
100/100
Authentic menu, artichoke asiago jalapeno gourmet cheese spread
Authentic Menu
100/100
Authentic menu, gourmet cheese spread, sundried tomato
Authentic Menu
100/100
Avocado Ranch Salad Kit
Trader Joe’s
100/100
Bacon & Aged Cheddar Mac & Cheese Sauce, Bacon & Aged Cheddar
Private selection
70/100
Bacon wrapped chicken with jalapeno peppers
Unknown
100/100
BBQ & Black Pepper Toscano Chopped Salad
Trader Joe's
100/100
BBQ Chicken Pizza
Trader Joe's
95/100
Bean & Cheese Burrito
Wild Fork
100/100
Bistro savory lorraine quiche
Unknown
80/100
Black Bean & Cheese Taquitos
Trader Joe's
100/100
Black Pepper & Blue Cheese Organic Grass-Fed Beef Burgers
Frontiere Natural Meats
100/100
Borgonzola
Unknown
100/100
Breaded Fried Ravioli
Trader Joe's
100/100
Brie Spread
Eiffel Tower
100/100
Brie, Emporium Selection
Aldi
100/100
Brioche Baguettes
Whole Foods,Whole Foods Market
100/100
Brioche rolls
Unknown
100/100
Broccoli cheddar soup
Trader Joes
100/100
BROCCOLI CHEDDAR SOUP
KIRKLAND Signature
100/100
Bruschetta-style stone baked flatbread, bruschetta-style
Unknown
100/100
Buffalo seasoned cauli-tots, buffalo seasoned
Unknown
100/100
Buffalo Style Chicken Meatballs with Monterey Jack Cheese
Trader Joe's
100/100
Buffalo Style Chicken Poppers
Trader Joe's
100/100
BURRATA Fresh Mozzarella Cheese Filled with Cream
Trader Joe's
100/100
Butter with Parmesan, Garlic & Herb
Trader Joe’s
100/100
Butternut Squash Italian Lasagna
Trader Joe's
100/100
BUTTERNUT SQUASH MAC & CHEESE BITES
TRADER JOE'S
100/100
Butternut squash Mac and cheese
Trader Joe’s
100/100
Caesar Style Salad Kit
Trader Joe's
100/100
Camembert
Aldi
100/100
cauli-tots
Unknown
100/100
Cauliflower Crust Vegetable Pizza
Good & Gather
100/100
Cauliflower Slims
Trader Joe's
100/100

Frequently Asked Questions

Is Microbial Enzyme safe to eat?

Microbial Enzyme has a safety score of 3/5. Always check with a healthcare provider if you have specific dietary concerns.

What products contain Microbial Enzyme?

Microbial Enzyme is found in 431 products in our database, spanning various food categories and brands.

What does Microbial Enzyme do in food?

Microbial Enzyme serves various technical functions in food manufacturing and processing.

Where does this ingredient safety data come from?

Safety data comes from the FDA's SAFFA (Substances Added to Food) database, CSPI (Center for Science in the Public Interest) ratings, and the OpenFoodFacts product database. Product counts reflect items cataloged in OpenFoodFacts.