L-glutamine

L-glutamine carries a safety score of 3/5 and appears in 248 indexed US food products.

Safety score 60.0%

3/5 from FDA SAFFA + CSPI Chemical Cuisine

How common is vs other flagged additives?

Number of indexed products containing each of the most common flagged additives — L-glutamine highlighted.

Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.

Caramel Coloring22612Red 4021595Yellow 518987Carrageenan17853Blue 116643Yellow 613560Sucralose10490L-glutamine248
Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.
FDA Status
Approved
Safety Score
3/5

Function

FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, NUTRIENT SUPPLEMENT

Safety Assessment

L-glutamine has a moderate safety profile (3/5). While approved for use, some studies or consumer advocacy groups have raised questions about certain aspects of this ingredient. Consumers who prefer caution may wish to limit intake.

What the Data Says About

L-glutamine currently appears in 248 products across the OpenFoodFacts catalog we index, which gives a concrete measure of its footprint on US grocery shelves. Our internal safety score of 3/5 synthesizes FDA Substances Added to Food (SAFFA) regulatory status — currently "Approved" — with the Center for Science in the Public Interest (CSPI) Chemical Cuisine classification. These two frameworks capture different questions: regulators ask whether exposure at typical intake is acceptable, while consumer-advocacy groups examine cumulative dietary load and vulnerable-population risk.

In food manufacturing, L-glutamine functions as a flavor enhancer, flavoring agent or adjuvant, nutrient supplement. That technical role explains why it recurs across many product categories — formulators select specific additives for stability, shelf life, color, or texture performance, and substitution is rarely a one-for-one swap when regulations or consumer preferences shift. Inspection and outbreak data often trace back to breakdown in the control of exactly these kinds of functional ingredients, either through contaminated batches, undisclosed substitutions, or labeling errors that trigger FDA-initiated recalls.

No specific concern flags are attached to L-glutamine in our current data snapshot beyond the regulatory and CSPI classifications above. That does not rule out individual sensitivity reactions, and anyone managing allergies, elimination diets, or chronic conditions should verify with a qualified healthcare professional before relying on population-level ratings.

Safety Profile at a Glance

Regulatory and safety classifications for L-glutamine
Source Classification Year
FDA SAFFA Approved 2024
CSPI Chemical Cuisine Not rated 2024
PlainFoodSafe Score 3/5 2026
Product footprint 248 products OpenFoodFacts

FDA SAFFA database, CSPI Chemical Cuisine ratings, OpenFoodFacts product index. See methodology.

Products Containing

Showing 50 of 248 products

100% Mass Gainer Chocolate Fudge Brownie
MuscleTech
80/100
100% Whey Protein
EMRALD LABS
60/100
Abbott, Juven, Tissue Building Powder, Orange, Orange
Abbott
85/100
Acuts Amino-charged Energy
ALLMAX
70/100
Advocare Vanilla Meal Replacement shake
Unknown
85/100
Amino Recovery
Unknown
100/100
Amino Whey Pro Advantage Non-denatured, Grass-fed Whey Protein
Natura Health Products
100/100
Aminolean
Unknown
85/100
AminoLean Energy
RSP
100/100
AminoLean Pre-Workout
Smart Sweets
100/100
AMPLIFY XL
PMD
70/100
Amplify xl
Unknown
70/100
BCAA Natural Grape
Sascha Fitness
100/100
BCAA Natural Lemon Lime
Sascha Fitness
100/100
BCAA Natural Mango Coconut
Sascha Fitness
100/100
BCAA Natural Pineapple
Sascha Fitness
100/100
BCAA Natural Watermelon
Sascha Fitness
100/100
Bcaa Stim Free
PMD
85/100
Bcaa/eaa Plus
1UP Nutrition
85/100
Big 100 Colossal Meal Replacement Bar
Met-Rx Nutrition Inc.
100/100
Big 100 Colossal Meal Replacement Bar
Met-Rx
100/100
BIG 100 CRISPY APPLE PIE
MET-Rx
100/100
Big 100 meal replacement bar
Met-Rx
90/100
Big 100 mint super crunch cookie
Met -RX
100/100
BIG 100 PEANUT BUTTER PRETZEL
MFY
90/100
BIG 100 SUPER COOKIE CRUNCH
MET-RX
100/100
BIG 100 SUPER COOKIE CRUNCH Meal Replacement Bar
MET-Rx
75/100
Big cookie crunch bars
Met Rx
100/100
Big100 Colossal Meal Replacement Bar
Met-Rx Nutrition Inc.
100/100
Biosteel, high performance sports drink
Biosteel
85/100
Celeryforce
Vimergy
100/100
CG5 Creatine + Glutamine
PMD
100/100
Choconut protein bar
Unknown
100/100
Citrus Energy Drink
XS
70/100
Classic Chocolate Protein Performance Chocolate Bar, Classic Chocolate
Unknown
100/100
Colon Cleanse
Garden Greens
100/100
Complete Meal Chocolate Caramel
Plantfusion
100/100
Complete Meal Chocolate Caramel
Plantfusion
100/100
Complete Meal Creamy Vanilla Bean
Plantfusion
100/100
Complete Meal Creamy Vanilla Bean
Plantfusion
100/100
Complete Protein
PlantFusion
100/100
Cookie dough!
Unknown
100/100
Crispy Apple Pie Meal Replacement Bar
Unknown
100/100
Cyclone Strength
maxi NUTRITION
85/100
Daily Electrolyte drink mix
Saltwtr
100/100
Daily Essential Nutrients
Hardy Nutritionals
100/100
Daily Micronutrient Bar
Healright
100/100
Dark & salty bars
Unknown
100/100
Designer Whey
Designer Wellness
100/100
Designer Whey Natural 100% Whey Protein Powder
Designer Wellness
100/100

Frequently Asked Questions

Is L-glutamine safe to eat?

L-glutamine has a safety score of 3/5. FDA status: Approved. Always check with a healthcare provider if you have specific dietary concerns.

What products contain L-glutamine?

L-glutamine is found in 248 products in our database, spanning various food categories and brands.

What does L-glutamine do in food?

L-glutamine is used as a flavor enhancer, flavoring agent or adjuvant, nutrient supplement in food products.

Where does this ingredient safety data come from?

Safety data comes from the FDA's SAFFA (Substances Added to Food) database, CSPI (Center for Science in the Public Interest) ratings, and the OpenFoodFacts product database. Product counts reflect items cataloged in OpenFoodFacts.