Disodium 5'-inosinate

Disodium 5'-inosinate carries a safety score of 3/5 and appears in 39 indexed US food products.

Safety score 60.0%

3/5 from FDA SAFFA + CSPI Chemical Cuisine

How common is vs other flagged additives?

Number of indexed products containing each of the most common flagged additives — Disodium 5'-inosinate highlighted.

Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.

Caramel Coloring22612Red 4021595Yellow 518987Carrageenan17853Blue 116643Yellow 613560Sucralose10490Disodium 5'-inosinate39
Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.
Safety Score
3/5

Safety Assessment

Disodium 5'-inosinate has a moderate safety profile (3/5). While approved for use, some studies or consumer advocacy groups have raised questions about certain aspects of this ingredient. Consumers who prefer caution may wish to limit intake.

What the Data Says About

Disodium 5'-inosinate currently appears in 39 products across the OpenFoodFacts catalog we index, which gives a concrete measure of its footprint on US grocery shelves. Our internal safety score of 3/5 synthesizes FDA Substances Added to Food (SAFFA) regulatory status with the Center for Science in the Public Interest (CSPI) Chemical Cuisine classification. These two frameworks capture different questions: regulators ask whether exposure at typical intake is acceptable, while consumer-advocacy groups examine cumulative dietary load and vulnerable-population risk.

Disodium 5'-inosinate serves one or more technical functions in food manufacturing — stabilization, flavor, preservation, or structural role — which explains its presence across multiple product categories in our database. Inspection and outbreak records frequently trace back to control failures around functional additives, whether through batch contamination, undisclosed substitutions, or labeling mismatches that trigger recall classifications by the FDA.

No specific concern flags are attached to Disodium 5'-inosinate in our current data snapshot beyond the regulatory and CSPI classifications above. That does not rule out individual sensitivity reactions, and anyone managing allergies, elimination diets, or chronic conditions should verify with a qualified healthcare professional before relying on population-level ratings.

Safety Profile at a Glance

Regulatory and safety classifications for Disodium 5'-inosinate
Source Classification Year
FDA SAFFA Not listed 2024
CSPI Chemical Cuisine Not rated 2024
PlainFoodSafe Score 3/5 2026
Product footprint 39 products OpenFoodFacts

FDA SAFFA database, CSPI Chemical Cuisine ratings, OpenFoodFacts product index. See methodology.

Products Containing

Showing 39 of 39 products

American Turkey
Cheetos
85/100
Assorted fish cake (oden set)
Unknown
95/100
Beef & Green Onion Dumpling
wei-chuan
100/100
Bonito & Seaweed Topping For Rice
Nagatanien Co. Ltd.
100/100
Chicken potstickers
Unknown
100/100
Cuttlefish Crackers
Dragonfly
75/100
Cuttlefish Flavoree Cookies MIAOW MIAOW
Unknown
100/100
Furikake katsuomirin
Urashima
100/100
Hi Tempura
Tao Kae Noi
100/100
Instant Noodles Beef Ball Flavor
Daily,Vina Acecook
70/100
Japanese style rice crackers
Unknown
100/100
Juzz's mee instant flat noodles developed by the singapore flour experts
Unknown
80/100
Liquid seasoning
Unknown
100/100
Lkk chilli bean sauce
Lee Kum Kee
100/100
Mi Chay Vegetarian Instant Noodle
Miliket Colusa
100/100
Nagasaki champon
Unknown
95/100
Nagatanien, Wasabi
Nagatanien Co. Ltd
100/100
Noodle Soup Base
Wismettac Asian Foods Inc.
100/100
Original Popping Corn Chips
Lotte
100/100
Pork & shrimp wonton
Unknown
75/100
Pre Steamed Vegetable & Pork Dumpling
Wei-Chuan
100/100
Pre-steamed vegetable & chicken gyoza dumplings
Wei-Chuan
100/100
Premium mix arare
Unknown
95/100
Premium Mixed Arare
Hawaiian Tradition
95/100
Premium Mixed Arare
Unknown
20/100
Pretz, Baked Snack Sticks
Glico
100/100
Sauce for mabo tofu
Lee Kum Kee
95/100
Seasoned bamboo shoots
Momoya
100/100
Seasoned Seaweed
Momoya
100/100
Seasoned Zhacai
Momoya
100/100
Sesame Sauce
Yi Shiang Processed Food Factory
100/100
Shirakiku, seasoned pollack roe spicy, karashi mentaiko
Shirakiku
100/100
Stewed Beef Noodle Soup With Tomato
Wei-Chuan
100/100
Surimi Snow Leg Style
Gadre
85/100
Sushi Bake
Costco
95/100
Tempura seaweed
Unknown
100/100
Thin Soy Sauce
Unknown
100/100
Vegetable Pre-Steamed Dumpling
Unknown
90/100
Yamaki Kappo Shirodashi Versatile Dashi Base
Unknown
100/100

Frequently Asked Questions

Is Disodium 5'-inosinate safe to eat?

Disodium 5'-inosinate has a safety score of 3/5. Always check with a healthcare provider if you have specific dietary concerns.

What products contain Disodium 5'-inosinate?

Disodium 5'-inosinate is found in 39 products in our database, spanning various food categories and brands.

What does Disodium 5'-inosinate do in food?

Disodium 5'-inosinate serves various technical functions in food manufacturing and processing.

Where does this ingredient safety data come from?

Safety data comes from the FDA's SAFFA (Substances Added to Food) database, CSPI (Center for Science in the Public Interest) ratings, and the OpenFoodFacts product database. Product counts reflect items cataloged in OpenFoodFacts.