Non-animal Enzymes

Non-animal Enzymes carries a safety score of 3/5 and appears in 172 indexed US food products.

Safety score 60.0%

3/5 from FDA SAFFA + CSPI Chemical Cuisine

How common is vs other flagged additives?

Number of indexed products containing each of the most common flagged additives — Non-animal Enzymes highlighted.

Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.

Caramel Coloring22612Red 4021595Yellow 518987Carrageenan17853Blue 116643Yellow 613560Sucralose10490Non-animal Enzymes172
Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.
Safety Score
3/5

Safety Assessment

Non-animal Enzymes has a moderate safety profile (3/5). While approved for use, some studies or consumer advocacy groups have raised questions about certain aspects of this ingredient. Consumers who prefer caution may wish to limit intake.

What the Data Says About

Non-animal Enzymes currently appears in 172 products across the OpenFoodFacts catalog we index, which gives a concrete measure of its footprint on US grocery shelves. Our internal safety score of 3/5 synthesizes FDA Substances Added to Food (SAFFA) regulatory status with the Center for Science in the Public Interest (CSPI) Chemical Cuisine classification. These two frameworks capture different questions: regulators ask whether exposure at typical intake is acceptable, while consumer-advocacy groups examine cumulative dietary load and vulnerable-population risk.

Non-animal Enzymes serves one or more technical functions in food manufacturing — stabilization, flavor, preservation, or structural role — which explains its presence across multiple product categories in our database. Inspection and outbreak records frequently trace back to control failures around functional additives, whether through batch contamination, undisclosed substitutions, or labeling mismatches that trigger recall classifications by the FDA.

No specific concern flags are attached to Non-animal Enzymes in our current data snapshot beyond the regulatory and CSPI classifications above. That does not rule out individual sensitivity reactions, and anyone managing allergies, elimination diets, or chronic conditions should verify with a qualified healthcare professional before relying on population-level ratings.

Safety Profile at a Glance

Regulatory and safety classifications for Non-animal Enzymes
Source Classification Year
FDA SAFFA Not listed 2024
CSPI Chemical Cuisine Not rated 2024
PlainFoodSafe Score 3/5 2026
Product footprint 172 products OpenFoodFacts

FDA SAFFA database, CSPI Chemical Cuisine ratings, OpenFoodFacts product index. See methodology.

Products Containing

Showing 50 of 172 products

Amy's cheddar shells and broccoli
Annie's
100/100
Annie's 25% Less Sodium Mac & Cheese Made with Organic Pasta
Annie's
100/100
Annie's cheddar cheesy smiles
Annie's
100/100
Annie's Classic Mild Cheddar Microwavable Macaroni and Cheese Micro Cup 2ct
Unknown
100/100
Annie's Deluxe Four Cheese Macaroni & Cheese Made with Organic Pasta
Annie's
100/100
Annie's Deluxe Rich & Creamy Shells & Classic Cheddar
Annie's
100/100
Annie's Deluxe White Cheddar Macaroni & Cheese Made with Organic Pasta
Unknown
100/100
Annie's Deluxe Whole Wheat & Cheddar Macaroni & Cheese Made with Organic Pasta
Unknown
100/100
Annie's Gluten Free Baked Cracker Cheddar Bunny Tails
Annie's
100/100
Annie's Gluten Free Cheddar Bunny Tails Baked Crackers
Unknown
100/100
Annie's Gluten Free Cheddar Bunny Tails Baked Snack Crackers
Unknown
100/100
Annie's Gluten Free White Cheddar Bunny Tails Baked Snack Cracker
Unknown
100/100
Annie's Homegrown Gluten Free Quinoa Rice Pasta & White Cheddar
Unknown
100/100
Annie's Homegrown Gluten Free Rice Pasta & Cheddar Micro Cup
Annie's Homegrown
100/100
Annie's Homegrown Gluten Free Rice Pasta & Cheddar Micro Cup 2 Pack
Unknown
100/100
Annie's Homegrown Gluten Free Rice Pasta and Cheddar Mac & Cheese 8 Count
Unknown
100/100
Annie's Homegrown Microwavable Real Aged Cheddar Macaroni & Cheese 5 Pack, Made with Organic Pasta
Unknown
100/100
Annie's Homegrown Microwavable White Cheddar Macaroni & Cheese 5 pack, Made with Organic Pasta.
Unknown
100/100
Annie's Homegrown Shells & White Cheddar Macaroni & Cheese 6pk, Made with organic Pasta
Unknown
100/100
Annie's Homegrown White Cheddar Macaroni & Cheese Micro Cup 12ct. Made with Organic Pasta
Unknown
100/100
Annie'S Homegrown, Cheesy Taco, Shells & Cheddar, Macaroni & Cheese, Macaroni & Cheese
Annie's homegrown
100/100
Annie's limited edition Mac & [extreme] cheese
Annie's
100/100
Annie's Organic All Stars
Unknown
100/100
Annie's Organic Bernie's Farm Macaroni and Cheese
Unknown
100/100
Annie's Organic Bunny Tails With Butter and Parmesan Macaroni & Cheese
Unknown
100/100
Annie'S Organic Cheddar Cheesy Smiles. Baked Puffed Corn
Annie's
100/100
Annie's organic cheesy smiles
Annie's
100/100
Annie's Organic Deluxe Creamy Cheddar Macaroni & Cheese
Unknown
100/100
Annie's Organic Elbow Pasta & Cheddar, 2018 Limited Edition Organic Wheat & Peas
Unknown
100/100
Annie's Organic Family Size Shells & White Cheddar Macaroni & Cheese
Unknown
100/100
Annie's Organic Grass Fed Real Aged Cheddar Macaroni & Cheese Microwavable Cup 12 Pack
Unknown
100/100
Annie's Organic Mac and Bees, Pollinator Pasta Shapes & Yummy Cheddar
Unknown
100/100
Annie's Organic Macaroni and Cheese, 12g Protein
Unknown
100/100
Annie's Organic Shells & White Cheddar Macaroni & Cheese 12 Pack
Unknown
100/100
Annie's Organic White Cheddar Bunny Tail Puffs
Unknown
100/100
Annie's Organic White Cheddar Bunny Tail Puffs
Unknown
100/100
Annie's Organic Whole Wheat Shells & White Cheddar Mac & Cheese
Annie's
100/100
Annie's puppies & kitties & white cheddar
Annie's
100/100
Annies Classic Cheddar
Annie's
100/100
Annies hmgrwn org gltn free rice pasta chdr
Unknown
100/100
Annies hmgrwn org gltn free rice shell pasta crmy white chdr
Unknown
100/100
Annies homegrown organic microwave macaroni and cheese cup
Annie's
100/100
Annies mac and cheese pasta and cheddar
Annie's
100/100
Annies organic all stars canned pasta in tomato
Unknown
100/100
Annies organic canned pasta bernie o s pasta
Annie's
100/100
Annies white cheddar Mac
Unknown
100/100
Annie’s Mickey and Friends Pasta and Cheddar
Annie's
100/100
Arthur Macaroni & Cheese
Annie's
100/100
Baked Snack Crackers, Organic White Cheddar Squares
Unknown
100/100
Baked white meat chicken layered with corn tortillas, cheese, tomatoes, onions, peppers, mild green chiles and cilantro casserole, baked chicken tortilla casserole
Unknown
100/100

Frequently Asked Questions

Is Non-animal Enzymes safe to eat?

Non-animal Enzymes has a safety score of 3/5. Always check with a healthcare provider if you have specific dietary concerns.

What products contain Non-animal Enzymes?

Non-animal Enzymes is found in 172 products in our database, spanning various food categories and brands.

What does Non-animal Enzymes do in food?

Non-animal Enzymes serves various technical functions in food manufacturing and processing.

Where does this ingredient safety data come from?

Safety data comes from the FDA's SAFFA (Substances Added to Food) database, CSPI (Center for Science in the Public Interest) ratings, and the OpenFoodFacts product database. Product counts reflect items cataloged in OpenFoodFacts.