L-histidine

L-histidine carries a source-backed screening score of 3/5 and appears in 45 indexed US food products.

Source-backed answer

L-histidine appears in 45 catalogued products. CSPI has no rating attached in this snapshot. Its FDA SAFFA status is “Approved.” Those source labels describe the ingredient; they do not establish whether a particular product, dose, allergy, or diet is safe.

45
catalogued products
#5,333
usage rank of 247,206
28
named brands represented
50%
average depth down ingredient lists

Catalog prevalence comes from Open Food Facts ingredient lists. FDA SAFFA and CSPI Chemical Cuisine labels are shown only when the source record contains them.

High-volume listing for L-histidine - usage rank #5,333

Usage rank
#5,333
of 247,206 ingredients that appear in at least one catalogued product, tied with 86 others that also appear in exactly 45 products.
Typical depth in an ingredient list
50%
Of the way down the captured list, averaged across the 45 products listing it (mean slot 16.6). L-histidine usually falls in the upper half of the list; this position does not measure its amount because source formatting, compound ingredients and labeling exceptions vary.

Ranks use Open Food Facts ingredient rows on this site’s refresh cycle. 247,206 ingredients with ≥1 product appearance enter the ranking. Prevalence and list depth are catalog facts, not toxicology.

What this page can and cannot answer

Separate this ingredient from its product neighborhood

This is a mixed product neighborhood: 16 of 45 records have some flagged component, while the rest do not. Compare ACTIVE Essential Amino Acid Blend; Amino K.e.m.; AMINO+ EAA/BCAA Strawberry Kiwi to see how surrounding formulations change; do not assign their 70–100 score range to L-histidine itself. The ingredient most often sits in the upper half of the list, and Dietary supplements supplies the most useful like-for-like starting point for a label review.

16 of 45 linked records have some flagged component

All 45 NOVA-classified records cluster most heavily in Group 4, while the first-category labels split across several shelves. That makes the 70–100 score spread more informative than the average alone: investigate the low end, identify the actual flagged row, and compare it with a similar unflagged formulation before drawing a conclusion.

Next check: pair one flagged product with a similar unflagged product from the same shelf category.

What else is usually in the same product as L-histidine

Across the 45 products on this site that list L-histidine, these flagged additives appear alongside it most often. The comparison column is how often each one appears across every product with a parsed ingredient list, so the two figures are measured over the same set. Sucralose shows up about 12.3x more often with L-histidine than in the catalogue at large.

Additive Shared products Share of L-histidine products Share of all products
Sucralose 15 33.3% 2.7%
Acesulfame Potassium 5 11.1% 1.8%

Co-occurrence describes what manufacturers formulate together. It is not a claim that these additives interact, and it carries no regulatory meaning. Counted over products with parsed ingredient lists; Open Food Facts, 2026-09-01.

Function

FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, NUTRIENT SUPPLEMENT

How do the sampled products compare?

Each point is one of the 16 sampled products listed below: its overall safety score against how many separately flagged ingredients its label carries. Bubble size is the number of ingredient rows the label actually resolved to.

Safety score vs. flagged-ingredient count for products containing L-histidine

Per-product safety score and flagged-ingredient count from the same sampled listings shown below. Bubble size = linked ingredient rows. Source: Open Food Facts labels x FDA SAFFA x CSPI Chemical Cuisine. 2×2 strategic matrix plotting 16 entities by Safety score (X) and Flagged ingredients on label (Y), with a crosshair dividing the plot into four quadrants. High score, still flaggedLow score, more flaggedHigh score, fewer flaggedLow score, fewer flagged 60708090100110 00.511.522.5 Safety score Flagged ingredients on label Safety score vs. flagged-ingredient count for products containing L-histidine
Per-product safety score and flagged-ingredient count from the same sampled listings shown below. Bubble size = linked ingredient rows. Source: Open Food Facts labels x FDA SAFFA x CSPI Chemical Cuisine.

High-volume peers for L-histidine

Top-decile company for L-histidine: 45 listings averaging 93.2/100.

Similar mean product score

Score-axis peers only, mean screening score among ingredients with ≥50 scored products, not a second count list.

Using the L-histidine evidence

Use the 45-product footprint and source labels as a starting point, then inspect the records most relevant to your question.

  • Open the product sample for L-histidine and read how the term sits on real packages. Open product sample
  • Compare another ingredient’s source-backed rating, FDA status, and product footprint. Open a peer record
  • Check the methodology for how FDA SAFFA, CSPI, and Open Food Facts rows are joined on this site. See source joins

This page describes published source classifications and product-label coverage. It is not dietary, allergy, or medical advice.

Frequently Asked Questions

Does L-histidine carry its own safety label in this catalog?

This is a mixed neighborhood: some linked products carry a separate flag while others do not. L-histidine itself carries and FDA SAFFA status "Approved" where the source record supplies them. Compare like-for-like products before treating the average screening score as an ingredient verdict.

Which product shelves show up most often with L-histidine?

L-histidine ranks in the top decile by product count (#5,333 of 247,206), appearing in 45 indexed products led by Dietary supplements. The sample list below is a slice of that footprint, not the full universe.

What does L-histidine do in food?

L-histidine is recorded as a flavor enhancer, flavoring agent or adjuvant, nutrient supplement in source technical-effect fields.

Regulatory status: FDA SAFFA (L-histidine). Safety ratings: CSPI Chemical Cuisine; product presence: Open Food Facts via PlainFoodSafe (September 2026). Figures are computed from those sources, no editor-typed counts. Methodology · State regulations.