Disodium Inosinate/disodium Guanylate

Disodium Inosinate/disodium Guanylate carries a safety score of 3/5 and appears in 37 indexed US food products.

Safety score 60.0%

3/5 from FDA SAFFA + CSPI Chemical Cuisine

How common is vs other flagged additives?

Number of indexed products containing each of the most common flagged additives — Disodium Inosinate/disodium Guanylate highlighted.

Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.

Caramel Coloring22612Red 4021595Yellow 518987Carrageenan17853Blue 116643Yellow 613560Sucralose10490Disodium Inosinate/disodium Guanylate37
Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.
Safety Score
3/5

Safety Assessment

Disodium Inosinate/disodium Guanylate has a moderate safety profile (3/5). While approved for use, some studies or consumer advocacy groups have raised questions about certain aspects of this ingredient. Consumers who prefer caution may wish to limit intake.

What the Data Says About

Disodium Inosinate/disodium Guanylate currently appears in 37 products across the OpenFoodFacts catalog we index, which gives a concrete measure of its footprint on US grocery shelves. Our internal safety score of 3/5 synthesizes FDA Substances Added to Food (SAFFA) regulatory status with the Center for Science in the Public Interest (CSPI) Chemical Cuisine classification. These two frameworks capture different questions: regulators ask whether exposure at typical intake is acceptable, while consumer-advocacy groups examine cumulative dietary load and vulnerable-population risk.

Disodium Inosinate/disodium Guanylate serves one or more technical functions in food manufacturing — stabilization, flavor, preservation, or structural role — which explains its presence across multiple product categories in our database. Inspection and outbreak records frequently trace back to control failures around functional additives, whether through batch contamination, undisclosed substitutions, or labeling mismatches that trigger recall classifications by the FDA.

No specific concern flags are attached to Disodium Inosinate/disodium Guanylate in our current data snapshot beyond the regulatory and CSPI classifications above. That does not rule out individual sensitivity reactions, and anyone managing allergies, elimination diets, or chronic conditions should verify with a qualified healthcare professional before relying on population-level ratings.

Safety Profile at a Glance

Regulatory and safety classifications for Disodium Inosinate/disodium Guanylate
Source Classification Year
FDA SAFFA Not listed 2024
CSPI Chemical Cuisine Not rated 2024
PlainFoodSafe Score 3/5 2026
Product footprint 37 products OpenFoodFacts

FDA SAFFA database, CSPI Chemical Cuisine ratings, OpenFoodFacts product index. See methodology.

Products Containing

Showing 37 of 37 products

American chop suey
Unknown
95/100
Beef base
Unknown
95/100
Beef gravy concentrate
Unknown
95/100
Beef meatballs with barbecue sauce
Unknown
95/100
Beef Shepherd's Pie
Big Y
95/100
Cheese sauce mix
Unknown
35/100
Chicken Base
Unknown
100/100
Chicken base
Unknown
100/100
Chicken base
Unknown
100/100
Chicken base
Minor's
100/100
Chicken base
Unknown
100/100
Chicken base
Unknown
100/100
Chicken base
Unknown
100/100
Chicken poblano firecrackers
Unknown
100/100
Chipotle braised beef
Unknown
95/100
Chunky grilled sirloin steak with hearty vegetables ready to serve soup, sirloin steak with hearty vegetables
Unknown
95/100
Clam chowder
Unknown
100/100
Clam chowder condensed
Unknown
100/100
Clam Chowder Soup
Fortun's
100/100
Concentrate demi glace sauce
Unknown
95/100
Demi Glace Sauce Concentrate
L. J. Minor Corp.
95/100
Firecrackers
Unknown
100/100
Fish cakes
Unknown
85/100
Fully cooked chicken marsala with cappelini and sunshine carrots, chicken marsala
Unknown
95/100
Ham and black bean torta sandwich
Unknown
85/100
Kettle cooked seafood gumbo
Unknown
95/100
Kings command foods fully cooked 0.5 ounce swedish meatballs, 2-5 pound bags of meatballs, 2-2 pound sauce packets in a 14 pound net weight master case.
Unknown
95/100
Minor's, beef gravy mix
Minor's
65/100
Minors, Turkey Base
L. J. Minor Corp.
100/100
Mushroom & asparagus risotto
Unknown
95/100
POT PIE
Unknown
85/100
Poultry gravy mix
Unknown
100/100
Sauce & Marinade
Got Jerk!
100/100
Sweet baby ray's, marinade & sauce, tequila lime
Sweet Baby Ray's, Sweet Baby Rays Inc.
100/100
Trio, alfredo sauce mix
Unknown
85/100
Trio, brown gravy mix
Unknown
65/100
Trio, chicken gravy mix
Unknown
100/100

Frequently Asked Questions

Is Disodium Inosinate/disodium Guanylate safe to eat?

Disodium Inosinate/disodium Guanylate has a safety score of 3/5. Always check with a healthcare provider if you have specific dietary concerns.

What products contain Disodium Inosinate/disodium Guanylate?

Disodium Inosinate/disodium Guanylate is found in 37 products in our database, spanning various food categories and brands.

What does Disodium Inosinate/disodium Guanylate do in food?

Disodium Inosinate/disodium Guanylate serves various technical functions in food manufacturing and processing.

Where does this ingredient safety data come from?

Safety data comes from the FDA's SAFFA (Substances Added to Food) database, CSPI (Center for Science in the Public Interest) ratings, and the OpenFoodFacts product database. Product counts reflect items cataloged in OpenFoodFacts.