Disodium Inosinate & Guanylate

Disodium Inosinate & Guanylate carries a safety score of 3/5 and appears in 89 indexed US food products.

Safety score 60.0%

3/5 from FDA SAFFA + CSPI Chemical Cuisine

How common is vs other flagged additives?

Number of indexed products containing each of the most common flagged additives — Disodium Inosinate & Guanylate highlighted.

Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.

Caramel Coloring22612Red 4021595Yellow 518987Carrageenan17853Blue 116643Yellow 613560Sucralose10490Disodium Inosinate & Guanylate89
Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.
Safety Score
3/5

Safety Assessment

Disodium Inosinate & Guanylate has a moderate safety profile (3/5). While approved for use, some studies or consumer advocacy groups have raised questions about certain aspects of this ingredient. Consumers who prefer caution may wish to limit intake.

What the Data Says About

Disodium Inosinate & Guanylate currently appears in 89 products across the OpenFoodFacts catalog we index, which gives a concrete measure of its footprint on US grocery shelves. Our internal safety score of 3/5 synthesizes FDA Substances Added to Food (SAFFA) regulatory status with the Center for Science in the Public Interest (CSPI) Chemical Cuisine classification. These two frameworks capture different questions: regulators ask whether exposure at typical intake is acceptable, while consumer-advocacy groups examine cumulative dietary load and vulnerable-population risk.

Disodium Inosinate & Guanylate serves one or more technical functions in food manufacturing — stabilization, flavor, preservation, or structural role — which explains its presence across multiple product categories in our database. Inspection and outbreak records frequently trace back to control failures around functional additives, whether through batch contamination, undisclosed substitutions, or labeling mismatches that trigger recall classifications by the FDA.

No specific concern flags are attached to Disodium Inosinate & Guanylate in our current data snapshot beyond the regulatory and CSPI classifications above. That does not rule out individual sensitivity reactions, and anyone managing allergies, elimination diets, or chronic conditions should verify with a qualified healthcare professional before relying on population-level ratings.

Safety Profile at a Glance

Regulatory and safety classifications for Disodium Inosinate & Guanylate
Source Classification Year
FDA SAFFA Not listed 2024
CSPI Chemical Cuisine Not rated 2024
PlainFoodSafe Score 3/5 2026
Product footprint 89 products OpenFoodFacts

FDA SAFFA database, CSPI Chemical Cuisine ratings, OpenFoodFacts product index. See methodology.

Products Containing

Showing 50 of 89 products

Asian Vegetables With Sweet Soy Seasoning
The Pictsweet Company
100/100
BANQUET - Cheeseburger Breadstick, 4.91 OZ
Unknown
95/100
Beef Jerky
Western Family
100/100
Beef Jerky
Publix Super Markets Inc.
100/100
Beef Jerky
7-Eleven Inc.
85/100
Beef Summer Sausage Snack Deli Bites
Johnsonville
85/100
Buffalo dressing
The Hvr Company
100/100
buttermilk ranch
Unknown
100/100
Cauliflower snack
Unknown
100/100
Ceviche
Unknown
95/100
Chicken fried rice
Unknown
95/100
Chicken pho noodles
Unknown
95/100
Chicken pot pie
Unknown
90/100
Coney island cheese sauce hot dog topping
Unknown
100/100
Cracked Pepper Ranch
Hidden Valley
100/100
Creole seasoning
Zatarain's
100/100
Cucumber Dressing
Hidden Valley, The Hvr Company
100/100
Deli bites summer sausage snack
Monogram Snacks Martinsville Llc
85/100
Deli Bites, Beef Summer Sausage Snack
Johnsonville
85/100
Dill pickle pork rinds
Unknown
100/100
Dressing
Hidden Valley, The Hvr Company
85/100
Dressing
The Hvr Company
100/100
Dry roasted & seasoned pistachios
Unknown
100/100
Family gourmet, ranch dressing & dip, buttermilk
Family Gourmet, Family Dollar Stores Inc.
100/100
Freeze dried buttermilk biscuits with gravy and pork patty crumbles, biscuits and gravy
Unknown
100/100
Gourmet Blends Chicken Stock Base
Spice Islands
75/100
Gyros bites
Unknown
100/100
Gyros slices
Unknown
100/100
Hardy Farms, Georgia Fried Peanuts
Hardy's Peanuts Inc.
100/100
Hardy farms, georgia fried peanuts, southern sriracha
Hardy Farms
100/100
Hidden Valley Ranch Dressing Bacon
Hidden Valley, The Hvr Company
85/100
Honey bbq sauce
Unknown
75/100
Instant broth chicken flavor packets, chicken
Gel Spice Co. Inc.
100/100
Jalapeno nacho pretzels
Unknown
75/100
Jumbo Meat Ravioli
Larosa's
95/100
Kettle cooked potato chips, sour cream & onion
Kettle, Krause Gentle Corporation
100/100
Light ranch dressing & dip
Hidden Valley, The Hvr Company
100/100
Marie callender's, steak pot pie
Unknown
95/100
Marinade Mix, Tequila Lime
Weber
100/100
New orleans style salmon cake mix, new orleans style
Zatarain's
95/100
New orleans style tuna cake mix, new orleans style
Unknown
95/100
Noodle, Soy Sauce Based Soup With Gourmet Vegetables
Crystal, Crystal Noodle
100/100
Pan Pasta
Red Baron
100/100
Philly cheese steak calzone
Unknown
100/100
Philly cheesesteak seasoned beef steak layered with a blend of melted cheeses, onions and red & green peppers in a crispy golden crust stuffed sandwiches, philly cheesesteak
Unknown
80/100
Philly Steak & Cheese Stuffed Sandwiches
America's Choice
80/100
Pizza
Palermo Villa Inc.
80/100
Popcorn
Unknown
85/100
Popcorn
Unknown
100/100
Poultry Gravy
Mccormick, Mccormick & Co Inc.
95/100

Frequently Asked Questions

Is Disodium Inosinate & Guanylate safe to eat?

Disodium Inosinate & Guanylate has a safety score of 3/5. Always check with a healthcare provider if you have specific dietary concerns.

What products contain Disodium Inosinate & Guanylate?

Disodium Inosinate & Guanylate is found in 89 products in our database, spanning various food categories and brands.

What does Disodium Inosinate & Guanylate do in food?

Disodium Inosinate & Guanylate serves various technical functions in food manufacturing and processing.

Where does this ingredient safety data come from?

Safety data comes from the FDA's SAFFA (Substances Added to Food) database, CSPI (Center for Science in the Public Interest) ratings, and the OpenFoodFacts product database. Product counts reflect items cataloged in OpenFoodFacts.