L-isoleucine

L-isoleucine carries a source-backed screening score of 3/5 and appears in 221 indexed US food products.

Source-backed answer

L-isoleucine appears in 221 catalogued products. CSPI has no rating attached in this snapshot. Its FDA SAFFA status is “Approved.” Those source labels describe the ingredient; they do not establish whether a particular product, dose, allergy, or diet is safe.

221
catalogued products
#1,823
usage rank of 247,206
76
named brands represented
40%
average depth down ingredient lists

Catalog prevalence comes from Open Food Facts ingredient lists. FDA SAFFA and CSPI Chemical Cuisine labels are shown only when the source record contains them.

L-isoleucine sits in the busiest tenth of the catalog (#1,823 / 247,206)

Usage rank
#1,823
of 247,206 ingredients that appear in at least one catalogued product, tied with 5 others that also appear in exactly 221 products, listed in more products than 99.3% of them.
Typical depth in an ingredient list
40%
Averaged label depth puts L-isoleucine in the upper half of the list (40% of list length, mean slot 11.4). Compound ingredients and OCR noise mean this cannot stand in for quantity.

Derived by this site from the ingredient lists of every catalogued product (Open Food Facts), recomputed on each data refresh. 247,206 ingredients have at least one appearance and are ranked here. Usage and list position describe prevalence, not safety.

What this page can and cannot answer

Audit the co-occurring flags first

63.3% of the linked products contain at least one separately flagged ingredient, making co-occurrence the dominant follow-up question. That figure does not identify L-isoleucine as the trigger. Open records such as 100% Mass Gainer Chocolate Fudge Brownie; 100% Pure Whey With Grass Fed Whey Isolates Vanilla Cream Slice Flavour; 7-Eleven Select Fusion Energy Drink Rockin' Rainbow and inspect which ingredient row carries the caution marker. The 84.0/100 product average is therefore a triage signal for this surrounding formulation set, not an ingredient verdict. Its 40% average label depth helps locate the term when checking the package.

63.3% of linked products contain a separately flagged ingredient

Processing is unusually concentrated here: Group 4 accounts for 220 of 220 NOVA-tagged records. That describes the surrounding products, not the substance. For a useful comparison, hold category and processing level constant, then inspect which named component changes alongside the caution flag; otherwise the product mix will confound the ingredient question.

Next check: open the lowest-scoring linked formulation and locate the exact caution-marked component.

What else is usually in the same product as L-isoleucine

Across the 221 products on this site that list L-isoleucine, these flagged additives appear alongside it most often. The comparison column is how often each one appears across every product with a parsed ingredient list, so the two figures are measured over the same set. Sucralose shows up about 22.6x more often with L-isoleucine than in the catalogue at large.

Sucralose: +58.4ppSucralose+58.4ppAcesulfame Potassium: +40.7ppAcesulfame Potassium+40.7ppCarrageenan: +0ppCarrageenan+0ppMonk fruit extract: +2.2ppMonk fruit extract+2.2pp
Percentage-point gap vs the catalogue baseline rate for each additive, L-isoleucine products only. Source: Open Food Facts ingredient lists.
Chart values as text

Unit: percentage points above/below baseline. Data current as of September 2026.

Sucralose
58.4pp
Acesulfame Potassium
40.7pp
Carrageenan
0pp
Monk fruit extract
2.2pp
Additive Shared products Share of L-isoleucine products Share of all products
Sucralose 135 61.1% 2.7%
Acesulfame Potassium 94 42.5% 1.8%
Carrageenan 10 4.5% 4.5%
Monk fruit extract 6 2.7% 0.5%

Co-occurrence describes what manufacturers formulate together. It is not a claim that these additives interact, and it carries no regulatory meaning. Counted over products with parsed ingredient lists; Open Food Facts, 2026-09-01.

Function

FLAVORING AGENT OR ADJUVANT, NUTRIENT SUPPLEMENT

How do the sampled products compare?

Each point is one of the 16 sampled products listed below: its overall safety score against how many separately flagged ingredients its label carries. Bubble size is the number of ingredient rows the label actually resolved to.

Safety score vs. flagged-ingredient count for products containing L-isoleucine

Per-product safety score and flagged-ingredient count from the same sampled listings shown below. Bubble size = linked ingredient rows. Source: Open Food Facts labels x FDA SAFFA x CSPI Chemical Cuisine. 2×2 strategic matrix plotting 16 entities by Safety score (X) and Flagged ingredients on label (Y), with a crosshair dividing the plot into four quadrants. High score, still flaggedLow score, more flaggedHigh score, fewer flaggedLow score, fewer flagged 60708090100110 00.511.522.5 Safety score Flagged ingredients on label Safety score vs. flagged-ingredient count for products containing L-isoleucine
Per-product safety score and flagged-ingredient count from the same sampled listings shown below. Bubble size = linked ingredient rows. Source: Open Food Facts labels x FDA SAFFA x CSPI Chemical Cuisine.

L-isoleucine vs other top-decile catalog footprints

Top-decile company for L-isoleucine: 221 listings averaging 84/100. Comparable product-count neighbours: Batter · Celery Juice · Cooked Grape Must.

Similar product count

Nearest other ingredients by Open Food Facts product count (floored at ≥50).

Similar mean product score

Mean product-score neighbours (≥50 scored products), kept separate from the product-count peers above.

What to do with this L-isoleucine record

221 product rows plus any FDA/CSPI fields on L-isoleucine are the evidence base — drill into the listings that matter for your decision.

  • Review the sampled product records that list L-isoleucine to see how the ingredient appears in actual labels. Browse linked labels
  • Place L-isoleucine next to “Celery Juice” (or another peer) using the same FDA/CSPI and prevalence fields. Compare a peer
  • Check the methodology for how FDA SAFFA, CSPI, and Open Food Facts rows are joined on this site. See source joins

This page describes published source classifications and product-label coverage. It is not dietary, allergy, or medical advice.

Frequently Asked Questions

How should I read safety signals when L-isoleucine sits in heavily flagged products?

63.3% of linked products contain at least one separately flagged ingredient, so the first task is locating which row carries the caution marker — not assuming L-isoleucine is the trigger. Where a source rating exists, L-isoleucine scores 3/5 on this site's screening scale with FDA SAFFA status "Approved". None of that replaces a product-, dose-, allergy-, or person-specific determination.

Which product shelves show up most often with L-isoleucine?

L-isoleucine ranks in the top decile by product count (#1,823 of 247,206), appearing in 221 indexed products led by Beverages and beverages preparations. The sample list below is a slice of that footprint, not the full universe.

What function does L-isoleucine serve when it appears beside other flagged additives?

L-isoleucine is recorded as a flavoring agent or adjuvant, nutrient supplement in source technical-effect fields. In high co-flag products, that function coexists with other caution-marked components — inspect the full list rather than isolating this role.

Regulatory status: FDA SAFFA (L-isoleucine). Safety ratings: CSPI Chemical Cuisine; product presence: Open Food Facts via PlainFoodSafe (September 2026). Figures are computed from those sources, no editor-typed counts. Methodology · State regulations.