Choline Chloride

Choline Chloride carries a safety score of 3/5 and appears in 455 indexed US food products.

Safety score 60.0%

3/5 from FDA SAFFA + CSPI Chemical Cuisine

How common is vs other flagged additives?

Number of indexed products containing each of the most common flagged additives — Choline Chloride highlighted.

Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.

Caramel Coloring22612Red 4021595Yellow 518987Carrageenan17853Blue 116643Yellow 613560Sucralose10490Choline Chloride455
Indexed products containing each flagged additive. Source: Open Food Facts ingredient lists × FDA SAFFA × CSPI Chemical Cuisine.
FDA Status
GRAS
Safety Score
3/5

Function

NUTRIENT SUPPLEMENT

Safety Assessment

Choline Chloride has a moderate safety profile (3/5). While approved for use, some studies or consumer advocacy groups have raised questions about certain aspects of this ingredient. Consumers who prefer caution may wish to limit intake.

What the Data Says About

Choline Chloride currently appears in 455 products across the OpenFoodFacts catalog we index, which gives a concrete measure of its footprint on US grocery shelves. Our internal safety score of 3/5 synthesizes FDA Substances Added to Food (SAFFA) regulatory status — currently "GRAS" — with the Center for Science in the Public Interest (CSPI) Chemical Cuisine classification. These two frameworks capture different questions: regulators ask whether exposure at typical intake is acceptable, while consumer-advocacy groups examine cumulative dietary load and vulnerable-population risk.

In food manufacturing, Choline Chloride functions as a nutrient supplement. That technical role explains why it recurs across many product categories — formulators select specific additives for stability, shelf life, color, or texture performance, and substitution is rarely a one-for-one swap when regulations or consumer preferences shift. Inspection and outbreak data often trace back to breakdown in the control of exactly these kinds of functional ingredients, either through contaminated batches, undisclosed substitutions, or labeling errors that trigger FDA-initiated recalls.

No specific concern flags are attached to Choline Chloride in our current data snapshot beyond the regulatory and CSPI classifications above. That does not rule out individual sensitivity reactions, and anyone managing allergies, elimination diets, or chronic conditions should verify with a qualified healthcare professional before relying on population-level ratings.

Safety Profile at a Glance

Regulatory and safety classifications for Choline Chloride
Source Classification Year
FDA SAFFA GRAS 2024
CSPI Chemical Cuisine Not rated 2024
PlainFoodSafe Score 3/5 2026
Product footprint 455 products OpenFoodFacts

FDA SAFFA database, CSPI Chemical Cuisine ratings, OpenFoodFacts product index. See methodology.

Products Containing

Showing 50 of 455 products

0070074575414
Unknown
100/100
2% reduced fat milk
Unknown
100/100
360 Total Care Infant Formula
Similac,Abbot
95/100
A.R. Added Rice Infant Formula
Enfamil
100/100
A.r. Added Rice Infant Formula Milk-based Powder With Iron
Enfamil
100/100
A2 Organic Infant Formula
HappyBABY
100/100
Actagain Strawberry Burst Flavour
AYMES
100/100
Advanced Nutrition Shake, Strawberry
Ensure
95/100
Alimentum hypoallergenic for food allergies and
Abbott
95/100
Apetito x-tra
Unknown
100/100
Apple Cinnamon
BRAINIAC
100/100
Apple Strawberry Spinach
BRAINIAC
100/100
Aptamil Care
Nutricia
100/100
Banana Cinnamon Oat
Little Brainiac
100/100
Banana Grow & Gain Therapeutic Nutrition, Banana
Abbott
95/100
Banana Original Nutritional Shake, Banana
Equate
65/100
Beef & Bison Recipe
Pure Balance
100/100
Beef Meal & Rice Recipe
Wholesome
100/100
Blue Buffalo Tastefuls
Blue Buffalo
100/100
Blueberry mini bagels
Unknown
100/100
Blueberry soft bagels made with whole grain
Wegmans
100/100
Boost 530
Boost
100/100
Boost Glucose Control
Boost
80/100
Boost Nutritional Drink
Nestle HealthScience
95/100
Bowl & basket
Unknown
80/100
Brain Squeezers
BRAINIAC
100/100
Brain Squeezers
BRAINIAC
100/100
Brain Squeezers 'Mega Apple'
BRAINIAC
100/100
Brain Squeezers Applesauce
BRAINIAC
100/100
Brain Squeezers Fruit Smoothies with Brain Nutrients Omega-3s + Choline
BRAINIAC
100/100
Brain Squeezies
Little BRAINIAC
100/100
Brain support power squares nut clusters
Unknown
100/100
Brainiac Mega Apple
Brainiac
100/100
Breakfast Blend
Little BRAINIAC Organics
100/100
Breakfast Blend
Little BRAINIAC
100/100
Cacao ready-to-drink meal
soylent
85/100
Cafe Vanilla Ready-to-drink meal
Soylent
85/100
Caramel
Premier Protein
65/100
Carrot Blueberry Smoothie
Little BRAINIAC
100/100
Cherry vanilla whole milk yogurt with brainpack
Unknown
100/100
Chicken & Beef Chunk In Gravy
Beefeaters
100/100
Chicken & Brown Rice Recipe
Nutro
100/100
chicken meal
Unknown
100/100
Childrens Nutritional Drink
Cvs Pharmacy
70/100
Chocolate caramel with sunflower seedbutter clarity manuka honey plus, seedbutter
Unknown
100/100
Chocolate complete nutritional drink, chocolate
Unknown
95/100
Chocolate Mint High Protein Shake
Premier Protein
65/100
Chocolate nutritional shake
Unknown
40/100
Chocolate Peanut Butter
Premier Protein
65/100
Chocolate Pediatric Shake
Meijer
70/100

Frequently Asked Questions

Is Choline Chloride safe to eat?

Choline Chloride has a safety score of 3/5. FDA status: GRAS. Always check with a healthcare provider if you have specific dietary concerns.

What products contain Choline Chloride?

Choline Chloride is found in 455 products in our database, spanning various food categories and brands.

What does Choline Chloride do in food?

Choline Chloride is used as a nutrient supplement in food products.

Where does this ingredient safety data come from?

Safety data comes from the FDA's SAFFA (Substances Added to Food) database, CSPI (Center for Science in the Public Interest) ratings, and the OpenFoodFacts product database. Product counts reflect items cataloged in OpenFoodFacts.